Investigators fed mice a high-fat, high-protein diet plan. While the animals did not put on weight, they established about 30% more arterial plaque than mice fed a high-fat, regular protein diet plan, reported Babak Razani, M.D., Ph.D., from Washington University, St. Louis.
In addition, specific amino acids in protein, such as leucine and arginine, assisted thwart the procedure that generally assists avoid plaque accumulation, Razani and associates discovered. This caused cell death, making the plaques more unsteady and more raising cardiovascular disease and stroke threat, they stated.
Based on these findings, Razani visualizes future research studies of these amino acids and their function in cardiovascular threat. “Leucine is particularly high in red meat, compared with, say, fish or plant sources of protein,” he included.
Full findings appear in Nature Metabolism.